陳秀珍老師基本資料

陳秀珍
助理教授
Email: ls850185@mail.ndmctsgh.edu.tw
電話: 26321181-217
學歷：中國醫藥學院藥學士
　　　國防醫學院藥理碩士
　　　國防醫學院哲學博士
經歷：藥物食品檢驗局技佐
　　　英國倫敦大學客座研究
　　　美國密西根大學客座研究
　　　英國巴斯大學客座研究
　　　國防醫學院兼任助理教授
　　　康寧醫護暨管理專科學校助理教授
專長：生理學、血管電生理學及敗血性休克致病機轉與藥物治療之研究
教授科目：生理學及生理學實驗、應用生理學、生理學研究技術、循環生理學、膳食療養　　　　　學及與微生物免疫學
興趣：教學與研究、登山、球類運動、閱讀
座右銘：零碎時間織美夢
E-mail：sjchen@knjc.edu.tw & ls850185@mail.ndmctsgh.edu.tw
Tel：26321181-217 & 87923100-18666/18648
校內外服務：國防醫學院暑期醫學研習營指導老師(91-)
台北市古亭國小家長會委員(88/08-89/06)
台北市古亭國小愛心媽媽和導護媽媽(88/08-)
台北市富水里第十鄰鄰長(91/01-91/12)
台北市童軍64團服務員(93/09-)
學術著作：
1. Chen, S. J. and M. H. Yen: Vascular reactivity in experimental septic shock. 國防醫學院, 1992
2. Chen, S. J., M.C. Chung, C. C. Wu and M. H. Yen: Role of endothelium in noise-induced hypertension. J. Med. Sci. 1992; 13: 179-188
3. Wu, C. C., S. J. Chen and M. H. Yen: Effects of noise on blood pressure and vascular reactivities. Clin. Exp. Pharmacol. Physiol. 1992; 19: 833-838
4. Yen, M.H., S.J. Chen and C.C. Wu: Role of endothelium-derived relaxing factor on vascular reactivity in endotoxin-induced shock. Chin. J. Physiol 1993; 36: 225-231
5. Wu, C. C., S. J. Chen and M. H. Yen: Different responses to acetylcholine in the presence of nitric oxide inhibitor in rat aortae and mesenteric arteries. Clin. Exp. Pharmacol. Physiol. 1993; 20: 405-412
6. Wu, C. C., S. J. Chen and M. H. Yen: Attenuation of endothelium-dependent relaxation in mesenteric artery during noise-induced hypertension. J. Biomed. Sci 1994; 1: 49-53
7. Chen, S. J., C. C. Wu and M. H. Yen: Alterations in vascular reactivity in intraperitoneal sepsis. J. Cardiovasc. Pharmacol. 1994; 24: 786-793
8. Wu, C.C., C. Szabo, S.J. Chen, C. Thiemermann and J.R. Vane: Activation of soluble guanylyl cyclase by a factor other than nitric oxide or carbon monoxide contributes to the vascular hyporeactivity to vasoconstrictor agents in the aorta of rats treated with endotoxin. Biochem. Biohpys. Res. Commun. 1994; 201: 436-422
9. Wu, C.C., S.J. Chen, C. Szabo, C. Thiemermann and J.R. Vane: Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock. Br. J. Pharmacol. 1995; 114: 1666-1672
10. Yen, M.H., S.J. Chen and C.C. Wu: Comparison of responses to aminoguanidine and N�-nitro-L-arginine methyl ester in the rat aorta. Clin. Exp. Pharmacol. Physiol. 1995; 22: 641-645
11. Wu, C.C., S.J. Chen and M.H. Yen: Loss of acetylcholine-induced relaxation by M3-receptor activation in mesenteric arteries of spontaneously hypertensive rats. J. Cardiovasc. Pharmacol 1997; 30: 245-252
12. Wu, C.C., S.J. Chen and M.H. Yen: Nitric oxide-independent activation of soluble guanylyl cyclase contributes to endotoxin shock in rats. Am. J. Physiol. 1998; 275: H1148-H1157
13. Wu, C.C., S.J. Chen and M.H. Yen: Cyclic GMP regulates cromakalim-induced relaxation in the rat aortic smooth muscle: role of cyclic GMP in KATP-channels. Life Sci. 1999; 64: 2471-2478
14. Chen, S.J., C.C. Wu and M.H. Yen: Role of nitric oxide and K+-channels in vascular hyporeactivity induced by endotoxin. Naunyn-Schmiedeberg's Arch. Pharmacol. 1999;359: 493-499
15. Wu, C.C., M.H. Liao, S.J. Chen and M.H. Yen: Pentoxifylline improves circulatory failure and survival in rodent models of endotoxaemia. Eur. J. Pharmacol. 1999; 373: 41-49
16. Wu, C.C., M.H. Liao, S.J. Chen and M.H. Yen: Tetramethylpyrazine prevents inducible NO synthase expression and improves survival in rodent models of endotoxic shock. Naunyn-Schmiedeberg's Arch. Pharmacol. 1999; 360: 435-444
17. Wu, C.C., M.H. Liao, S.J. Chen, T.C. Chou, A. Chen and M.H. Yen: Terbutaline attenuates the circulatory failure and mitigates mortality in rodents with endotoxemia. SHOCK 2000; 14: 60-67
18. Chen, S.J., C.C. Wu, S.N. Yang, C.I. Lin and M.H. Yen: Abnormal activation of K+ channels in aortic smooth muscle of rats with endotoxic shock: electrophysiological and functional evidence. Br. J. Pharmacol. 2000; 131: 213-222
19. Chen, S.J. and M.H. Yen: Role of NO and K+ channels in vascular hyporeactivity in rats with endotoxin shock. 國防醫學院 2000
20. Chen, S.J., C.C. Wu, S.N. Yang, C.I. Lin and M.H. Yen: Hyperpolarization contributes to vascular hyporeactivity in rats with endotoxic shock. Life Sci. 2000; 68: 659-668
21. Chen, S.J.*, C.C. Wu and M.H. Yen: Exercise training activates KCa channels and enhances nitric oxide production in rat mesenteric artery and thoracic aorta. J. Biomed. Sci. 2001; 8: 248-255
22. Chen, S.J. and C.C. Wu*: Functional comparison of isothioureas on nitric oxide synthase isoforms in rat thoracic aortas. J. Med. Sci. 2002; 22: 119-126
23. Wu, J.Y., W.J. Liaw, C. Tzao, S.J. Chen, J.H. Wang and C.C. Wu*: Comparison of terbutaline and dobutamine in rats with endotoxemia. Chin. J. Physiol 2002; 45: 155-162
24. Liao, W.J., C. Tzao, J.Y. Wu, S.J. Chen, J.H. Wang and C.C. Wu*: Inhibition by terbutaline of nitric oxide and superoxide anion levels of endotoxin-induced organs injury in the anesthetized rat. Shock 2003; 19: 281-288
25. Chen, S.J., K.H. Chen, R.C. Webb, M.H. Yen and C.C. Wu*: Abnormal activation of Na+-K+ pump in aortas from rats with endotoxaemia. Naunyn-Schmiedeberg's Arch. Pharmacol. 2003; 368: 57-62
26. Chen, K.H., S.J. Chen* and C.C. Wu*: In comparison of sodium pump regulation between thoracic aortas and mesenteric arteries in rats. J. Med. Sci. 2004; 24: 19-26
27. Wu, C.C.*, S.J. Chen and C.J. Garland: NO and KATP-channels underlie endotoxin-induced smooth muscle hyperpolarization in rat mesenteric resistance arteries. Br. J. Pharmacol. 2004; 142: 479-484
得獎或優良事蹟：
行政院衛生署藥物食品檢驗局績優人員
台灣藥理學會優秀論文獎